The movement of blood all through our our bodies is an advanced course of. Particularly, the valves in our veins play an important function as a result of they permit blood to movement again to the center from different components of the physique. Typically, nonetheless, there are issues with these valves, together with a situation known as power venous insufficiency, or CVI, which impacts one-third of adults in the US.
With CVI, the valves within the leg veins turn into broken and don’t correctly ship blood again to the center. As a substitute, the veins fill with blood. That is very true when an individual stands, which will increase strain within the veins, inflicting swelling within the legs and ankles; it might additionally result in varicose veins, leg ulcers, and fixed leg ache.
Whereas there have been surgical remedies for CVI that focus on superficial (or near the pores and skin’s floor) veins, there hasn’t been a remedy for deep valvular illness, which impacts the big veins deep inside in our our bodies. Now, Yale Faculty of Medication researchers are attempting to alter that.
Yale is collaborating in a medical trial often known as SAVVE, which stands for Surgical Antireflux Venous Valve Endoprosthesis. Throughout this process, surgeons will implant a bioprosthesis—a small, steel body that comprises a porcine (i.e., from a pig) cardiac valve—into the femoral vein within the thigh. The implant stops blood from flowing again to the legs when it ought to solely journey in a single path—towards the center.
“Our hope is that we are able to truly get the affected person virtually to a treatment, in order that they not must cope with the excessive venous strain you see in power venous insufficiency,” says Raul J. Guzman, MD, a Yale Medication vascular and endovascular surgeon.
On this video, Yale Medication specialists focus on the SAVVE process and the way it can positively affect look after sufferers with power venous insufficiency.