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Taking vitamin D supplements may affect your weight and height, new research suggests. According to the study, people who are overweight and taking these supplements, compared to those with a low body mass index, experienced a small increase in vitamin D and other related indicators.

The study is a re-analysis VITAL test, active intake of vitamin D or marine omega-3 supplements is a major project to reduce the risk of cancer and cardiovascular disease in the elderly. The randomized, placebo-controlled trial was led by researchers at Brigham and Women’s Hospital in Massachusetts, which is affiliated with Harvard University. Overall, there was no significant effect of either type of supplement on these outcomes. However, some evidence suggests that vitamin D supplementation in people with a BMI below 25 (a BMI between 18.5 and 25 is considered “normal”) is associated with a lower risk of cancer and autoimmune disease. Cancer death.

To better understand this link, some of the same researchers decided to study blood samples taken from more than 16,000 volunteers over the age of 50 who participated in the experiment. These samples allowed them to look at people’s total vitamin D levels and other vitamin D biomarkers, such as metabolic products and calcium, before the study began. About 2,700 of these volunteers returned for follow-up blood tests two years later.

Regardless of group, people’s levels of vitamin D and these biomarkers increased after supplementation. But this increase was significantly more pronounced in people with a BMI over 25, who were overweight and obese. This hydration effect was also seen in people with low vitamin D levels at baseline, meaning they would benefit most from supplementation. They were the team’s breakthrough. Published Open Tuesday on JAMA Network.

“After two years, we observed dramatic differences, which corresponded to a higher BMI response to vitamin D supplementation,” said study author Deirdre Tobiah, associate epidemiologist in the Brigham Department of Preventive Medicine. press release from Harvard. “This may have clinical implications and may explain some of the observed differences of vitamin D supplementation in obesity.”

Why this could happen, the researchers suggest two possible theories. For example, high body fat can cause excess vitamin D – a fat-soluble vitamin – to be released from a person’s bloodstream and stored. Liver problems associated with obesity can prevent people from absorbing vitamin D efficiently..

But this is just one study.And more research is needed to confirm the patterns shown here. But the authors say their findings may ultimately lead to a reevaluation of the pros and cons of vitamin D supplements. And how to improve usability for people across the board. For example, people with a higher BMI may need higher doses of vitamin D to achieve the same benefits seen in people with a lower body weight.

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